Dr. Albert Stezin Sunny
Scientist
Biosketch
Dr. Albert Stezin Sunny is a clinician- scientist specializing in movement disorders and cognitive neurodegeneration. After receiving his MBBS from Christian Medical College, Ludhiana, he was awarded the Indian Council of Medical Research’s Talent Search MD-PhD fellowship to pursue a PhD in Clinical Neuroscience and Neurology at NIMHANS, Bangalore. His clinical and doctoral training focused on Parkinson’s disease, Atypical parkinsonism, Cerebellar ataxia, and other Genetic movement disorders. He also holds a Post-Graduate diploma in Clinical Geriatrics and Neurorehabilitation.
After working as a Clinical Specialist in Movement Disorders and Neurology, he joined the Centre for Brain Research (CBR) as a Scientific Officer. He leads and coordinates research activities into Parkinson’s disease and age-related cognitive-motor dysfunction. He is also in-charge of the Gait Lab (Cognitive-Motor Control Laboratory).
Adopting a multidisciplinary approach, Dr. Stezin integrates expertise in gait mechanics, advanced multimodal imaging, and non-invasive brain stimulation to explore the intricacies of cognitive and motor dysfunction in aging and neurodegenerative disorders. With over 50 peer-reviewed publications and other academic accolades, he remains dedicated to bridging clinical sciences and research, driving innovation to advance the understanding and management of movement and cognitive disorders.
Projects
Dr. Albert Stezin Sunny is actively involved in several research projects at CBR:
Gait and Postural analysis in Tata Longitudinal Study of Aging (TLSA) and the Srinivaspura Aging, Neuro Senescence and COGnition (SANSCOG) studies, funded by TATA trusts and Pratiksha Trust.
Young and Late-Onset Parkinson’s disease (YLOPD), funded by SKAN Research Trust. This is a longitudinal study attempts to unravel the underlying Clinical and Genetic differences in Early- and Late-onset of Parkinson’s disease (PD), especially with emphasis on motor and non-motor symptoms. (Role: Co-Investigator)
Understanding Progression and Natural history of patients with Atypical Parkinsonism (ATPARK), funded by Pratiksha Trust- Extra-Mural Support for Transformational Aging Brain Research (EMSTAR). (Role: Co-Investigator)
Non-invasive brain stimulation for cognitive enhancement in elderly with MCI- a randomised controlled trial, funded by CBR Intramural support (Role: Principal Investigator)
Exploring Gait Variability in Ageing and Neurodegeneration using a Prefrontal Cognitive Reverse Model, funded by CBR Intramural support (Role: Principal Investigator)
In addition to research, Dr. Stezin serves as CBR’s Biosafety and Occupational health officer.
Full list:
Google scholar: https://scholar.google.com/citations?hl=en&user=cdu2D1kAAAAJ
PubMed: https://pubmed.ncbi.nlm.nih.gov/?term=albert+stezin)
Stezin A, Sathe GJ, Gajbhiye A, Bharadwaj S, Ghose V, Bellad A, Malo PK, Holla V, Hegde S, Bharath RD, Saini J, Jain S, Yadav R, Pandey A, Pal PK. Dysregulated Cerebrospinal Fluid Proteome of Spinocerebellar Ataxia Type 2 and its Clinical Implications. Movement Disorders. 2024 May 20. doi: 10.1002/mds.29834.
Sandhya G, Monisha S, Singh S, Stezin A, Diwakar L, Issac TG. Hyperhomocysteinemia and its effect on ageing and language functions – HEAL study. Scientific Reports. 2024 Aug 29;14(1):20101. doi: 10.1038/s41598-024-69818-1. PMID: 39209902.
Mensegere A, Singh S, Stezin A, Sundarakumar JS, Issac TG. Effect of early menopause on cognition and brain morphology in an Urban Indian Cohort. Alzheimer’s and Dementia. 2024 Aug;20(8):5607-5616. doi: 10.1002/alz.14069. Epub 2024 Jul 1. PMID: 38946683.
Dash S, Kamble N, Stezin A, et al. Imaging Markers of Multiple System Atrophy and Their Association With Disease Severity: A Cross-Sectional Study. Cureus 16(8): e67896. doi:10.7759/cureus.67896
Singh S, Malo PK, Stezin A, Mensegere AL, Issac TG. Alteration in amygdala subfield volumes and their association with cognition in mild cognitive impairment. Journal of Neurology. 2024 Jun 15. doi: 10.1007/s00415-024-12500-3. Epub ahead of print. PMID: 38879703.
Ghosh A, S M, Stezin A, Diwakar L, Issac TG. Prevalence and patterns of vitamin D deficiency and its role in cognitive functioning in a cohort from South India. Scientific Reports. 2024 May 16;14(1):11215. doi: 10.1038/s41598-024-62010-5.
Sadhana Singh, Palash Kumar Malo, Albert Stezin, Abhishek L. Menesgere, Thomas Gregor Issac, Hippocampal subfields volume changes and its correlation with memory functions in patients with mild cognitive impairment, Aging and Health Research, 2024. doi.org/10.1016/j.ahr.2024.100183.
Bhattacharya A, Stezin A, Kamble N, Bhardwaj S, Yadav R, Pal PK. Abnormal cortical excitability in patients with spinocerebellar ataxia type 12. Parkinsonism and Related Disorders, 2024 Mar;120:106002. doi: 10.1016/j.parkreldis.2024.106002. Epub 2024 Jan 9.
Mahale RR, Stezin A, Prasad S, Kamble N, Holla VV, Netravathi M, Yadav R, Pal PK. Clinical Spectrum, Radiological Correlation and Outcome of Movement Disorders in Wilson’s Disease. Tremor and Other Hyperkinetic Movements (N Y). 2023 Oct 9;13:37. doi: 10.5334/tohm.794. PMID: 37840995; PMCID: PMC10573579.
Stezin A, Pal PK. Treatable Ataxias: How to Find the Needle in the Haystack? Journal of Movement Disorders. 2022 Sep 7. doi: 10.14802/jmd.22069.
Sundarakumar JS*, Stezin A*, Abhishek ML, SANSCOG & TLSA Collaborators, Ravindranath V. Rural-urban and gender differences in metabolic syndrome in the aging population from southern India: Two parallel, prospective cohort studies. EClinicalMedicine (Lancet). 2022;47:101395.
Holla VV, Neeraja K, Stezin A, Prasad S, Surisetti BK, Netravathi M, Kamble N, Yadav R, Pal PK. Utility of Clinical Exome Sequencing in Dystonia: A Single-Center Study From India. Journal of Movement Disorders. 2022 Mar 16. doi: 10.14802/jmd.21146.
Naskar A, Stezin A, Dharmappa A, Hegde S, Philip M, Kamble N, Saini J, Sandhya K, Tatu U, Yadav R, Pal PK, Alladi PA. Fibrinogen and Complement Factor H Are Promising CSF Protein Biomarkers for Parkinson’s Disease with Cognitive Impairment-A Proteomics-ELISA-Based Study. ACS Chemical Neuroscience. 2022 Feb 24. doi: 10.1021/acschemneuro.2c00019
Stezin A, Bhardwaj S, Hegde S, Jain S, Bharath RD, Saini J, Pal PK. Cognitive impairment and its neuroimaging correlates in spinocerebellar ataxia 2. Parkinsonism and Related Disorders. 2021 Apr;85:78-83.
Stezin A, Bhardwaj S, Khokhar S, Hegde S, Jain S, Bharath RD, Saini J, Pal PK. In-vivo microstructural white matter changes in early spinocerebellar ataxia 2. Acta Neurologica Scandinavica 2020 Oct 8. doi: 10.1111/ane.13359.
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Centre for Brain Research
Indian Institute of Science Campus
CV Raman Avenue
Bangalore 560012, India.
