CBR Biomarker Centre of Excellence
The long-term goal of CBR is to enable ‘healthy aging’ through significant contribution to minimising the burden of neurodegenerative diseases. CBR is presently working on developing a composite biomarker for early detection of dementia and design scalable interventions to prevent/postpone dementia. Towards this, the Centre integrates expertise in neuroscience, clinical research, genomics, data science, and engineering to advance early diagnosis, prevention, and intervention strategies. CBR’s large-scale cohort studies, multidisciplinary research, and commitment to innovative partnerships place it at the forefront of aging brain research in India.
CBR has embarked on setting up a Biomarker Centre of Excellence in collaboration with the UK Dementia Research Institute (UK DRI) and with support from Gates Ventures. This ambitious initiative aims to establish a sophisticated platform for the discovery and validation of neurodegenerative disease biomarkers. In addition to plasma biomarkers, the Centre will also explore digital biomarkers to build a more comprehensive understanding of disease onset and progression.
A unique strength of this Centre of Excellence is that it will function under the scientific guidance of Professor Henrik Zetterberg (UK DRI and University of Gothenburg), a globally recognised pioneer in biomarker research, and Professor Siddharthan Chandran, Director of the UK DRI, both of whom are Visiting Faculty Members at CBR. By working closely with Professors Zetterberg and Chandran, the Centre will integrate the state-of-the-art in fluid biomarker assays, high-throughput proteomics, and AI-driven analytics with unique, diverse cohorts from India and the UK in order to accelerate breakthroughs in early diagnosis. The Centre of Excellence will foster cross-institutional partnerships, training, and knowledge exchange to build capacity and advance global brain health research.
Opportunities at the CBR Biomarker Centre of Excellence
The CBR Biomarker Centre of Excellence is envisioned as a state-of-the-art hub at the forefront of translational neuroscience. We are inviting motivated and outstanding individuals to join us in this transformative journey. Multiple positions are open, providing an opportunity to be part of impactful research in biomarker science and contribute to the Centre’s mission in promoting healthy brain aging.
Now accepting applications for:
Lead – Proteomics, Biomarker Centre of Excellence
Job description
The Lead for Proteomics will provide strategic, scientific, and operational leadership for the Biomarker Centre of Excellence (CoE). Therefore, this role requires a combination of scientific expertise, strategic foresight, team management, and collaborative engagement. Besides overseeing research projects and mentoring a multidisciplinary team, the Lead will ensure rigorous quality standards for biomarker research and serve as the primary liaison to internal and external partners in this endeavour. The Lead will report to the Director, CBR.
Key responsibilities
- Cooperate with the CBR leadership in formulating and implementing the CoE’s scientific vision, research strategy, and long-term roadmap
- Oversee the design, execution, and evaluation of biomarker discovery, validation, and translational projects
- Formulate and maintain requisite standard operating procedures, quality assurance processes, and risk management frameworks
- Monitor advances and trends in science and technology to ensure the CoE stays at the leading edge of biomarker research
- Mentor a multidisciplinary team including research scientists, postdoctoral researchers, and technicians and support their professional development
- Oversee the CoE’s operational and financial management, including budgets, procurement, and reporting to various stakeholders
- Ensure compliance with scientific, ethical, and data governance standards
- Collaborate with imaging and digital biomarkers teams to create multi-modal biomarker profiles
- Foster strong linkages with international networks and maintain active engagement with the UK DRI Fluid Biomarker Lab to ensure global alignment and collaborative growth
- Build and nurture cordial relationships with collaborators and potential partners including research centres, academic institutions, clinical partners, technology providers, and vendor organisations
- Represent the CoE in national and international meetings, disseminate research findings through publications and presentations
- Contribute proactively to the broader vision of CBR, including capacity-building, outreach, and public engagement initiatives.
Qualifications
Essential
- PhD and notable postdoctoral experience in proteomics/ biomarker research, neuroscience, molecular biology, clinical chemistry, or a related field
- Proven track record of independent research excellence (as evidenced by peer-reviewed publications and research grants) and leadership in biomarker or translational science
- Deep understanding of biomarker assay technologies, validation strategies, and data interpretation
- Significant experience managing and mentoring research teams, including scientists, technicians, and administrative staff
- Strong organisational, strategic planning, and problem-solving skills
- Excellent interpersonal skills and ability to foster collaborations across disciplines and geographies
Desirable
- Experience leading or coordinating large-scale, multi-centric, collaborative projects
- Experience in technology evaluation, vendor management, research agreements, and contract negotiation
- Recognised contributions to scientific advisory boards/panels, expert committees, and professional societies
- Familiarity with AI-driven data analytics, biobanking, and digital health tools.
Salary and benefits
- Competitive salary commensurate with qualifications and relevant experience
- Access to world-class research infrastructure and cross-institutional training opportunities
- Direct engagement and collaboration with UK DRI researchers, Health Data Research UK (HDR UK), and other leaders in biomarker science and neurodegeneration research
- Opportunity to interface with the Indian Institute of Science’s vibrant, interdisciplinary research ecosystem spanning engineering, life sciences, and data science
- Support for overall professional development
- Additional benefits as per CBR policies.
Application process
Interested candidates should submit the following to jobs[at]cbr-iisc.ac.in with ‘Application: Lead – Proteomics, CBR Biomarker Centre of Excellence’ as the email subject line:
- A detailed CV (max. 5 pages)
- Cover letter outlining suitability for the role and vision for the CBR Biomarker Centre of Excellence (max. 2 pages)
- Contact details of at least 3 professional referees
Applications will be reviewed on a rolling basis until the position is filled. Only shortlisted candidates will be contacted for further discussion.
CBR reserves the right to modify, withdraw, or close this announcement at any time. CBR also reserves the right not to fill the position if no suitable candidate is identified. All appointments will be subject to verification of academic qualifications, relevant work experience, and satisfactory reference checks.
Start of employment
The position is available immediately; the start date is negotiable.
Contact
Queries may be addressed to jobs[at]cbr-iisc.ac.in
Lead – Digital Biomarkers, Biomarker Centre of Excellence
Job description
The Lead for Digital Biomarkers will spearhead the scientific direction, operational execution, and strategic expansion of the digital biomarker initiatives of the Centre of Excellence (CoE). This role requires robust expertise in digital health technologies and AI/ML and the ability to translate digital endpoints into impactful clinical research for neurodegenerative and cerebrovascular conditions. The Lead will oversee discovery, validation, and integration of digital biomarkers within broader translational workflows. The Lead will report to the Director of CBR.
Key responsibilities
- Cooperate with the CBR leadership in formulating and implementing the CoE’s scientific vision, research strategy, and long-term roadmap
- Design, oversee, and validate digital biomarker projects across community and clinical cohorts
- Formulate and maintain requisite standard operating procedures, quality assurance processes, and risk management frameworks
- Stay informed of global trends in digital health and data-driven monitoring, integrating emerging tools into the CoE’s portfolio
- Mentor a multidisciplinary team including data scientists, engineers, clinician researchers, and deployment specialists and support their professional development
- Oversee the CoE’s operational and financial management (including budgets, procurement, and reporting to various stakeholders) related to digital biomarker pipelines
- Ensure compliance with data privacy, regulatory, and ethical standards governing digital health in India and beyond
- Collaborate with fluid biomarkers and imaging teams to create multi-modal biomarker profiles
- Foster strong linkages with international networks and maintain active engagement with the UK DRI Fluid Biomarker Lab to ensure global alignment and collaborative growth
- Build and nurture cordial relationships with collaborators and potential partners including research centres, academic institutions, clinical partners, technology providers, and vendor organisations
- Represent the CoE in national and international meetings, disseminate research findings through publications and presentations
- Contribute proactively to the broader vision of CBR, including capacity-building, outreach, and public engagement initiatives.
Qualifications
Essential
- PhD (or equivalent) in digital health, data science, computer science, biomedical engineering, or related discipline
- Proven track record of independent research excellence (as evidenced by peer-reviewed publications and research grants) and leadership in digital biomarker development and validation
- Proficiency in AI/ML algorithms
- Familiarity with regulatory frameworks relevant to digital health tools
- Significant experience managing and mentoring research teams, including scientists, engineers, and administrative staff
- Strong organisational, strategic planning, and problem-solving skills
- Excellent interpersonal skills and ability to foster collaborations across disciplines and geographies
Desirable
- Experience leading or coordinating large-scale, multi-centric, collaborative projects
- Experience in technology evaluation, vendor management, research agreements, and contract negotiation
- Experience overseeing app and sensor platforms, device integration protocols, and data governance systems
- Recognised contributions to scientific advisory boards/panels, expert committees, and professional societies
Salary and benefits
- Competitive salary commensurate with qualifications and relevant experience
- Access to world-class research infrastructure and cross-institutional training opportunities
- Direct engagement and collaboration with UK DRI researchers, Health Data Research UK (HDR UK), and other leaders in biomarker science and neurodegeneration research
- Opportunity to interface with the Indian Institute of Science’s vibrant, interdisciplinary research ecosystem spanning engineering, life sciences, and data science
- Support for overall professional development
- Additional benefits as per CBR policies.
Application process
Interested candidates should submit the following to jobs[at]cbr-iisc.ac.in with ‘Application: Lead –Digital Biomarkers, CBR Biomarker Centre of Excellence’ as the email subject line:
- A detailed CV (max. 5 pages)
- Cover letter outlining suitability for the role and vision for the CBR Biomarker Centre of Excellence (max. 2 pages)
- Contact details of at least 3 professional referees
Applications will be reviewed on a rolling basis until the position is filled. Only shortlisted candidates will be contacted for further discussion.
CBR reserves the right to modify, withdraw, or close this announcement at any time. CBR also reserves the right not to fill the position if no suitable candidate is identified. All appointments will be subject to verification of academic qualifications, relevant work experience, and satisfactory reference checks.
Start of employment
The position is available immediately; the start date is negotiable.
Contact
Queries may be addressed to jobs[at]cbr-iisc.ac.in
Facility Coordinator, Biomarker Centre of Excellence
Job description
The Facility Coordinator will ensure smooth and efficient day-to-day operations of the Biomarker Centre of Excellence (CoE). Reporting to the Director of CBR and working closely with Lead – Proteomics and Lead – Digital Biomarkers, this role combines administrative oversight, operational support, and coordination across research and technical teams.
Key responsibilities
- Oversee logistics for lab space allocation, sample reception, inventory, and equipment maintenance
- Coordinate vendor interactions, servicing, and procurement of reagents/supplies
- Maintain detailed databases for equipment, freezer stock, consumables, and sample tracking; track and report facility usage metrics
- Prepare quotes, costings, and monitor expenditures related to projects and core facility operations
- Liaise with finance team on invoicing, purchase orders, and financial reporting
- Develop and maintain SOPs, risk assessments, biosafety documentation, and quality control logs.
- Coordinate and document ethical clearances, data governance compliance, and health & safety certifications
- Facilitate onboarding, training, and work allocation for staff in consultation with Leads
- Support multidisciplinary teams to optimize facility utilisation
- Support facility representation in meetings, audits, and periodic reviews
- Foster strong linkages with international networks and maintain active engagement with the UK DRI Fluid Biomarker Lab to ensure global alignment and collaborative growth
Qualifications
Essential
- Master’s degree (Science, Engineering, Management or related field)
- Laboratory or core facility administrative experience
- Proficiency in inventory systems, procurement workflows, and financial tracking
- Awareness of biosafety, ethical, and equipment compliance standards.
- Strong organisational and multitasking abilities.
- Excellent communication and interpersonal skills, with capacity to liaise across teams and senior stakeholders
Desirable
- Experience within a biomarker, proteomics, or clinical research facility
- Familiarity with digital health platforms or imaging workflows
- Exposure to grant-funded project coordination and financial reporting
- Ability to contribute to process improvements and facility efficiency initiatives.
Salary and benefits
- Competitive salary commensurate with qualifications and relevant experience
- Access to world-class research infrastructure and cross-institutional training opportunities
- Opportunity to interface with the Indian Institute of Science’s vibrant, interdisciplinary research ecosystem spanning engineering, life sciences, and data science
- Additional benefits as per CBR policies.
Application process
Interested candidates should submit the following to jobs[at]cbr-iisc.ac.in with ‘Application: Facility Coordinator, CBR Biomarker Centre of Excellence’ as the email subject line:
- A detailed CV (max. 3 pages)
- Cover letter outlining suitability for the role (max. 1 page)
- Contact details of at least 2 professional referees
Applications will be reviewed on a rolling basis until the position is filled. Only shortlisted candidates will be contacted for further discussion.
CBR reserves the right to modify, withdraw, or close this announcement at any time. CBR also reserves the right not to fill the position if no suitable candidate is identified. All appointments will be subject to verification of academic qualifications, relevant work experience, and satisfactory reference checks.
Start of employment
The position is available immediately; the start date is negotiable.
Contact
Queries may be addressed to jobs[at]cbr-iisc.ac.in
Research Scientist – Biomarker Centre of Excellence (Multiple positions)
Job description
The Research Scientist will join the multidisciplinary team at the CBR Biomarker Centre of Excellence to advance discovery and validation of fluid biomarkers relevant to neurodegenerative diseases. The role will entail designing and conducting experiments, analysing large-scale biomarker data, and collaborating closely with national and international partners. The Research Scientist will also contribute to maintaining high scientific and quality standards within the Centre and play an active role in capacity building, knowledge exchange, and dissemination of research findings. This position will report to the Lead, Biomarker Centre of Excellence.
Key responsibilities
- Design and implement experiments focused on proteomics, immunoassays, and other fluid biomarker technologies
- Contribute to data analysis and interpretation, including integration with clinical and imaging data from large-scale cohort studies
- Maintain rigorous documentation and adhere to established standard operating procedures and quality control protocols
- Collaborate with colleagues across disciplines, including neuroscience, clinical research, data science, and engineering
- Participate in joint projects and regular scientific discussions with UK Dementia Research Institute and other international partners
- Foster strong linkages with international networks and maintain active engagement with the UK DRI Fluid Biomarker Lab to ensure global alignment and collaborative growth
- Present research findings at internal and external meetings; contribute to high-quality publications in peer-reviewed journals
- Assist with procurement, equipment maintenance, and coordination of research activities within the Centre
- Contribute proactively to the broader vision of CBR, including capacity-building, outreach, and public engagement initiatives.
Qualifications
Essential
- PhD in proteomics, biomarker research, molecular biology, biochemistry, neuroscience, or a related field
- Demonstrated research expertise in proteomic technologies (e.g., mass spectrometry, immunoassays) and biomarker data analysis
- Proficiency in data handling and statistical analysis relevant to biomarker research
- Strong publication record in relevant peer-reviewed journals
- Commitment to collaborative, interdisciplinary research and ability to work effectively in a team
Desirable
- Experience working with large-scale, multi-centric projects/clinical or cohort datasets
- Knowledge in AI or machine learning methods applied to biomarker data
- Familiarity with biobanking protocols and data governance standards
Salary and benefits
- Competitive salary commensurate with qualifications and relevant experience
- Access to world-class research infrastructure and cross-institutional training opportunities
- Direct engagement and collaboration with UK DRI researchers, Health Data Research UK (HDR UK), and other leaders in biomarker science and neurodegeneration research
- Opportunity to interface with the Indian Institute of Science’s vibrant, interdisciplinary research ecosystem spanning engineering, life sciences, and data science
- Support for overall professional development and participation in scientific meetings and conferences
- Additional benefits as per CBR policies.
Application process
Interested candidates should submit the following to jobs[at]cbr-iisc.ac.in with ‘Application: Research Scientist – CBR Biomarker Centre of Excellence’ as the email subject line:
- A detailed CV (5 pages maximum)
- Cover letter highlighting relevant experience, research interests, and motivation to join the Biomarker Centre of Excellence (2 pages maximum)
- Contact details of at least 3 professional referees
Applications will be reviewed on a rolling basis until the position is filled. Only shortlisted candidates will be contacted for further discussion.
CBR reserves the right to modify, withdraw, or close this announcement at any time. CBR also reserves the right not to fill the position if no suitable candidate is identified. All appointments will be subject to verification of academic qualifications, relevant work experience, and satisfactory reference checks.
Start of employment
The position is available immediately; the start date is negotiable.
Contact
Queries may be addressed to jobs[at]cbr-iisc.ac.in
Research Technician – Biomarker Centre of Excellence (Multiple positions)
Job description
The Research Technician will support biomarker discovery and validation projects by performing laboratory assays, maintaining high standards of data quality, and ensuring that sample handling, processing, and reporting are carried out according to best practices. The role requires meticulous laboratory work, proactive problem-solving, and close collaboration with the multidisciplinary team at CBR and external partners including the UK DRI. The Research Technician will report to the Lead, Biomarker Centre of Excellence.
Key responsibilities
- Receive, catalogue, and appropriately store biological samples for biomarker studies
- Plan and execute measurements of fluid biomarkers in coordination with the Lead, Research Scientist, and other team members
- Maintain compliance with data governance, biosafety, and ethical standards and update laboratory standard operating procedures (SOPs), risk assessments, and quality control logs
- Ensure accurate, complete, and timely recording and reporting of experimental data
- Monitor and manage laboratory inventory and consumables; assist in procurement
- Troubleshoot assay and equipment issues; coordinate with service engineers as needed
- Participate actively in collaborative discussions and data review sessions
- Foster strong linkages with international networks and maintain active engagement with the UK DRI Fluid Biomarker Lab to ensure global alignment and collaborative growth
- Contribute proactively to the broader vision of CBR, including capacity-building, outreach, and public engagement initiatives.
Qualifications
Essential
- Bachelor’s degree in Biomedical Sciences, Biochemistry, Molecular Biology, Neuroscience, or a related field or substantial equivalent laboratory experience
- Practical experience with immunoassays and relevant lab technologies (e.g., ELISA, Simoa, MSD)
- Strong general laboratory competence (sample handling, pipetting, centrifugation, calibration)
- Excellent attention to detail, time management, and organisational skills to meet strict timelines
- Proficiency in IT tools (MS Office, data entry, electronic lab notebooks)
- Clear oral and written communication skills; ability to document procedures meticulously
- Ability to work both independently with minimal supervision and collaboratively in a multidisciplinary research environment.
Desirable
- Experience running large-scale biomarker assays and troubleshooting assay variability
- Interest in neurodegenerative disease research and translational biomarker science
- Awareness of AI/data analytics integration into biomarker workflows.
Salary and benefits
- Competitive salary commensurate with qualifications and experience.
- Access to world-class research infrastructure and cross-institutional collaborations (e.g., UK DRI, HDR UK)
- Opportunity to interface with the Indian Institute of Science’s vibrant, interdisciplinary research ecosystem spanning engineering, life sciences, and data science
- Support for overall professional development
- Additional benefits as per CBR policies.
Application process
Interested candidates should submit the following to jobs[at]cbr-iisc.ac.in with ‘Application: Research Technician – CBR Biomarker Centre of Excellence’ as the email subject line:
- Detailed CV (max. 4 pages)
- Cover letter summarising relevant experience and motivation for the role (max. 1 page)
- Contact details of at least 2 professional referees
Applications will be reviewed on a rolling basis until the position is filled. Only shortlisted candidates will be contacted. CBR reserves the right to modify or close this announcement at any time and may choose not to fill the position if no suitable candidate is identified. All appointments are subject to verification of academic qualifications, work experience, and satisfactory references.
Start of employment
The position is available immediately; the start date is negotiable.
Contact
Queries may be addressed to jobs[at]cbr-iisc.ac.in
Data Scientist – Biomarker Centre of Excellence (Multiple positions)
Job description
The Data Scientist will play a central role in analysing and integrating complex biomarker datasets to advance discovery and validation of neurodegenerative disease biomarkers. This role requires expertise in data science, statistical modelling, and AI/ML approaches, combined with an understanding of biological and clinical contexts. The Data Scientist will collaborate closely with laboratory scientists, clinicians, and international partners, including the UK Dementia Research Institute, to extract meaningful insights from large-scale fluid biomarker, multi-omics, clinical, and imaging data. The Data Scientist will report to the Lead, Biomarker Centre of Excellence.
Key responsibilities
- Develop and apply statistical, machine learning, and computational models to analyse biomarker, proteomic, and clinical datasets
- Integrate multimodal data from fluid biomarkers, genomics, imaging, and clinical assessments to identify predictive and diagnostic signatures
- Collaborate with research scientists and technicians to design data analysis plans and ensure rigorous data curation, cleaning, and quality control
- Lead the development and maintenance of secure, well-documented data pipelines, databases, and dashboards for internal and collaborative use
- Stay updated on methodological advances in AI/ML, bioinformatics, and biomarker analytics, and help translate these into the Centre’s workflows
- Foster strong linkages with international networks and maintain active engagement with the UK DRI Fluid Biomarker Lab to ensure global alignment and collaborative growth
- Contribute proactively to the broader vision of CBR, including capacity-building, outreach, and public engagement initiatives.
Qualifications
Essential
- Master’s or PhD in Data Science, Bioinformatics, Biostatistics, Computer Science, Computational Biology, or a related quantitative discipline
- Strong programming skills and familiarity with relevant data science libraries
- Proficiency in statistical analysis, data visualisation, and data management and ability to translate complex data insights into biological interpretations
- Strong problem-solving skills and ability to work both independently and collaboratively in multidisciplinary teams
Desirable
- Demonstrable experience analysing large-scale biological or clinical datasets, preferably biomarker or omics data
- Strong understanding of data governance, privacy regulations, and ethical considerations in biomedical research
Salary and benefits
- Competitive salary commensurate with qualifications and relevant experience
- Access to world-class research infrastructure and cross-institutional training opportunities
- Direct engagement and collaboration with UK DRI researchers, Health Data Research UK (HDR UK), and other leaders in biomarker science and neurodegeneration research
- Opportunity to interface with the Indian Institute of Science’s vibrant, interdisciplinary research ecosystem spanning engineering, life sciences, and data science
- Support for professional development and participation in scientific meetings and workshops
- Additional benefits as per CBR policies
Application process
Interested candidates should submit the following to jobs[at]cbr-iisc.ac.in with ‘Application: Data Scientist – CBR Biomarker Centre of Excellence’ as the email subject line:
- Detailed CV (max. 5 pages)
- Cover letter highlighting relevant experience, motivation for the role, and how your skills can advance the Centre’s mission (max. 2 pages)
- Contact details of at least 3 professional referees
Applications will be reviewed on a rolling basis until the position is filled. Only shortlisted candidates will be contacted for further discussion. CBR reserves the right to modify, withdraw, or close this announcement at any time. CBR may also choose not to fill the position if no suitable candidate is identified. All appointments are subject to verification of academic qualifications, relevant work experience, and satisfactory reference checks.
Start of employment
The position is available immediately; the start date is negotiable.
Contact
Queries may be addressed to jobs[at]cbr-iisc.ac.in
